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Catalog Number Size Price
LS-C3765-50 50 µg $558 
Antibody

Monoclonal Mouse anti‑Human APC Antibody (aa1‑433, IHC, WB) LS‑C3765

Monoclonal Mouse anti‑Human APC Antibody (aa1‑433, IHC, WB) LS‑C3765

Antibody:
APC Mouse anti-Human Monoclonal (aa1-433) Antibody
Application:
IHC, IHC-Fr, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$558
LS-C3765-50
Toll Free North America
(800) 227-6666
For Research Use Only

Overview

Antibody:
APC Mouse anti-Human Monoclonal (aa1-433) Antibody
Application:
IHC, IHC-Fr, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
APC antibody LS-C3765 is an unconjugated mouse monoclonal antibody to human APC (aa1-433). Validated for IHC and WB.
Target
Human APC
Synonyms
APC | Adenomatosis polyposis coli | Adenomatous polyposis coli | BTPS2 | Deleted in polyposis 2.5 | DP2 | DP2.5 | FPC | GS | Protein APC | PPP1R46 | DP3
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Immunogen
Synthetic peptide corresponding to aa1-433 N-Terminus fragment of human APC (Adenomatous Polyposis Coli gene Chr 5q) (coupled to maltose binding protein). Cellular localization: cytoplasmic and nuclear.
Epitope
aa1-433
Specificity
Recognizes the N-terminal region of the human APC protein. Epitope Mapping: Performed by differential in vitro expression of the N-terminal region of the APC gene by using the protein truncation test. Found to bind to APC in the region between aa135-422 (exon 2-3). Species cross-reactivity: Does not cross-react with mouse.
Applications
  • IHC
  • IHC - Frozen
  • Western blot
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Suitable for use in Immunohistochemistry and Western Blot. Immunohistochemistry: Acetone fixed, frozen sections. Positive control: Colon cell line HCT116, SW480 and SW837 extracts.
Presentation
PBS, pH 7.2, 40% Glycerol
Storage
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About APC
P25054 NM_000038 NP_000029.2

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 11/21/2024