Target
Human ANXA5 / Annexin V
Synonyms
ANXA5 | ANX5 | Anchorin CII | Calphobindin I | CBP-I | ENX2 | PP4 | RPRGL3 | Lipocortin V | Thromboplastin inhibitor | VAC-alpha | Vascular anticoagulant-alpha | PAP-I | Annexin A5 | Annexin V | Annexin-5 | Endonexin II
Reactivity
Human, Mouse, Rat
(tested or 100% immunogen sequence identity)
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Immunogen
Human partial recombinant protein (aa2-320).
Specificity
Human ANXA5 / Annexin V
Applications
- IHC
- IHC - Paraffin (0.5 - 1 µg/ml)
- IHC - Frozen (0.5 - 1 µg/ml)
- Western blot (0.5 - 1 µg/ml)
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Usage
Annexin V or A5 has been proposed to play a role in the inhibition of blood coagulation by competing for phosphatidylserine binding sites with prothrombin and also to inhibit the activity of phospholipase A1. This protein is an anticoagulant protein, it can form a shield around negatively-charged phospholipid molecules, the formation of an Annexin V shield blocks the entry of phospholipids into coagulation (clotting) reactions. Annexin AV can also act as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.
Presentation
Lyophilized from PBS, 2.5% BSA, 0.025% sodium azide.
Reconstitution
Reconstitute in sterile distilled water.
Storage
Prior to reconstitution, 4°C. Following reconstitution store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee