Target
Human ABCB1 / MDR1 / P Glycoprotein
Synonyms
ABCB1 | ABC20 | Abcb1b | CLCS | Colchicin sensitivity | CD243 | IBD13 | gp170 | MDR1 | Multidrug resistance protein 1 | P glycoprotein | P-glycoprotein 1 | P-GP | CD243 antigen | PGY1
Reactivity
Human, Primate
(tested or 100% immunogen sequence identity)
Non-Reactivity
Mouse, Rat
Clonality
IgG2a
Monoclonal
Conjugations
Phycoerythrin
Purification
Protein G purified
Immunogen
Mouse Balb/c 3T3 fibroblasts transfected with human CD243 cDNA.
Specificity
Specifically recognizes an extracellular conformational epitope of human CD243 also known as MDR1 and Pgp (P-glycoprotein), a transmembrane protein and member of the ABC transporter (ATP-binding cassette) family, which acts as an active efflux pump for a diverse range of lipophillic compounds. Does not cross-react with mouse or rat.
Usage
Suitable for use in Flow cytometry. Flow cytometry: neat Use 10 ul of the suggested working dilution to label 1x1E6 cells in 100ul. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
Lyophilized PBS, pH 7.4, 0.09% Sodium Azide, 1% BSA
Reconstitution
Sterile 40-50% glycerol, ddH2O
Storage
Store at 4°C. Do not freeze.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About ABCB1 / MDR1 / P Glycoprotein