Target
Human ALK3 / BMPR1A
Synonyms
BMPR1A | 10q23del | ALK3 | ALK-3 | BMP type-1A receptor | BMPR-1A | CD292 | CD292 antigen | Activin receptor-like kinase 3 | ACVRLK3 | SKR5
Reactivity
Human
(tested or 100% immunogen sequence identity)
Immunogen
Synthetic peptide derived from an internal region of the human BMPR-1A (bone morphogenetic protein receptor type 1A, Serine/threonine protein kinase receptor R5 (SKR5), activin receptor-like kinase-3 (ALK-3)), which differs from mouse and rat BMPR-1A by one nonconservative amino acid replacement.
Specificity
Recognizes human BMPR-1A at ~60 kD. Reactivity has been confirmed with human SK-OV-3, NGP96, SKMEL-19, SK-MEL-37, A375, MeWo cell lysates and mouse ovary homogenates. Based on amino acid sequence homology, reactivity with rat is also expected. Species sequence homology: rat.