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| Catalog Number | Size | Price |
|---|---|---|
| LS-C743909-1 | 1 ml (1 mg/ml) | $1,063 |
Polyclonal Rabbit AGE Antibody LS‑C743909
Polyclonal Rabbit AGE Antibody LS‑C743909
Antibody:
AGE Rabbit Polyclonal Antibody
Application:
ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
AGE Rabbit Polyclonal Antibody
Application:
ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
AGE antibody LS-C743909 is an unconjugated rabbit polyclonal antibody to human AGE. Validated for ELISA.
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Modifications
Unmodified
Immunogen
Advanced Glycation End Products /BSA/HSA
Applications
- ELISA (1 µg/ml)
Usage
This antibody is suitable for the detection of different AGE products in tissues, tissue extracts and body fluids. Long-term incubation of proteins with glucose leads, through Schiff's base and Amadori rearrangement products, to the formation of advanced glycation end products (AGE) which are characterized by fluorescence, brown color and inter- and intra-molecular cross-linking. Recent immunological studies using anti-AGE antibodies demonstrated the presence of AGE in (i) human lens, (ii) renal proximal tubules in patients with diabetic nephropathy and chronic renal failure, (iii) atherosclerotic lesions of arterial walls, (iv) ß2-microglobulin of carpal tunnel amyloid fibril deposits in patients with hemodialysis-related amyloidosis and (v) brain tissues of patients with Alzheimer's disease. These results suggested the potential role of AGE in normal aging and age-enhanced disease processes. Advanced Glycation End Products (AGE), cross-reactivity BSA and HSA <1%.
Presentation
50 mM Phosphate Buffer, pH 7.15, 0.85% NaCl, 0.05% Sodium Azide
Storage
Store at -20°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
Publications (0)
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Featured Products
Species:
Human, All species
Applications:
ICC, Western blot, Immunoprecipitation
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 12/25/2024
Date Requested: 12/25/2024
