Target
Human ADIPOR1/Adiponectin Receptor 1
Synonyms
ADIPOR1 | Adiponectin receptor 1 | Adiponectin Receptor | Adiponectin receptor protein 1 | CGI-45 | CGI45 | ACDCR1 | TESBP1A | PAQR1
Reactivity
Human
(tested or 100% immunogen sequence identity)
Conjugations
Horseradish Peroxidase.
Also available
Unconjugated or conjugated with
FITC,
Biotin.
Immunogen
Recombinant Human Adiponectin receptor protein 1 protein (1-63AA)
Specificity
Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism (PubMed:25855295, PubMed:12802337). Required for normal glucose and fat homeostasis and for maintaining a normal body weight. ADIPOQ-binding activates a signaling cascade that leads to increased AMPK activity, and ultimately to increased fatty acid oxidation, increased glucose uptake and decreased gluconeogenesis. Has high affinity for globular adiponectin and low affinity for full-length adiponectin (By similarity).