Target
Human Adiponectin
Synonyms
ADIPOQ | Adiponectin | ADPN | ACDC | ADIPQTL1 | APM-1 | APM1 | ACRP30 | Gelatin-binding protein 28 | GBP28 | Gelatin-binding protein
Reactivity
Human
(tested or 100% immunogen sequence identity)
Immunogen
Recombinant human adiponectin purified from E. coli.
Specificity
Recognizes human adiponectin, (also known as Acrp30), a 244 amino acid major adipokine secreted into the bloodstream from adipose tissue to modulate metabolism, including glucose regulation and fatty acid catabolism. Unlike most other adipokines, adiponectin is secreted exclusively by differentiating adipocytes at reduced levels during obesity. The serum level of adiponectin is inversely correlated with BMI (body mass index) of an individual, and has an anti-inflammatory action, playing an important role in type II diabetes (insulin sensitivity) and atherosclerosis.