Target
Human ACOX1 / ACOX
Synonyms
ACOX1 | ACOX | Acyl-CoA oxidase 1, palmitoyl | Acyl-coa oxidase, peroxisomal | AOX | SCOX | PALMCOX | Palmitoyl-CoA oxidase
Reactivity
Human
(tested or 100% immunogen sequence identity)
Conjugations
Horseradish Peroxidase.
Also available
Unconjugated or conjugated with
FITC,
Biotin.
Immunogen
Recombinant human Peroxisomal acyl-coenzyme A oxidase 1 protein (113-273AA)
Specificity
Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. Isoform 1 shows highest activity against medium-chain fatty acyl-CoAs and activity decreases with increasing chain length. Isoform 2 is active against a much broader range of substrates and shows activity towards very long-chain acyl-CoAs. Isoform 2 is twice as active as isoform 1 against 16-hydroxy-palmitoyl-CoA and is 25% more active against 1,16-hexadecanodioyl-CoA.