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| Catalog Number | Size | Price |
|---|---|---|
| LS-B1815-50 | 50 µg (1 mg/ml) | $460 |
1 of 2
2 of 2
IHC‑plus™ Polyclonal Rabbit anti‑Human ACKR3 / CXCR7 Antibody (aa100‑150, IHC, WB) LS‑B1815
IHC‑plus™ Polyclonal Rabbit anti‑Human ACKR3 / CXCR7 Antibody (aa100‑150, IHC, WB) LS‑B1815
Note: This antibody replaces LS-C47399
Antibody:
ACKR3 / CXCR7 Rabbit anti-Human Polyclonal (aa100-150) Antibody
Application:
IHC, IHC-P, WB, Flo
Reactivity:
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
ACKR3 / CXCR7 Rabbit anti-Human Polyclonal (aa100-150) Antibody
Application:
IHC, IHC-P, WB, Flo
Reactivity:
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit
Format:
Unconjugated, Unmodified
Specifications
Description
CXCR7 antibody LS-B1815 is an unconjugated rabbit polyclonal antibody to CXCR7 (ACKR3) (aa100-150) from human. It is reactive with human, mouse, rat and other species. Validated for Flow, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 3 publications.
Target
Human ACKR3 / CXCR7
Synonyms
ACKR3 | Chemokine orphan receptor 1 | CMKOR1 | CXCR7 | CXC-R7 | GPRN1 | RDC1 | RDC-1 | CXCR-7 | G-protein coupled receptor 159 | GPR159
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit
(tested or 100% immunogen sequence identity)
Predicted
Xenopus (at least 90% immunogen sequence identity)
Clonality
IgG
Polyclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Immunogen
A synthetic peptide (QHNQWPMGELTC) corresponding amino acids 106-117 of human CXCR7/RDC1 was used as the immunogen, GenBank NP_064707.1. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Bat, Dog, Horse, Rabbit, Pig, Opossum (100%); Platypus, Xenopus (92%); Turkey (83%).
Epitope
aa100-150
Specificity
A portion of amino acids 100-150 of human RDC1.
Applications
- IHC
- IHC - Paraffin (10 µg/ml)
- Western blot (4 - 6 µg/ml)
- Flow Cytometry (1 - 10 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Immunohistochemistry: LS-B1815 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B1815 was determined to be 10 ug/ml.
Presentation
Tris-Glycine, 0.05% Sodium Azide
Storage
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About ACKR3 / CXCR7
Validation
Anti-CXCR7 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-CXCR7 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
See More About...
LSBio Ratings
IHC-plus™ ACKR3 / CXCR7 Antibody (aa100-150) for IHC, WB/Western, Flow LS-B1815 has an LSBio Rating of
Publications (4.2)
Laboratory Validation Score (4)
Learn more about The LSBio Ratings Algorithm
Publications (3)
Heteromerization of chemokine (C-X-C motif) receptor 4 with alpha 1A/B-adrenergic receptors controls alpha 1-adrenergic receptor function. Vana PG, Chavan TS, Brueggemann LI, Byron KL, Tarasova NI, Volkman BF, Gaponenko V, Majetschak M. Proceedings of the National Academy of Sciences of the United States of America. Mar; (PLA; Human, Rat)
New Insights into Mechanisms and Functions of Chemokine (C-X-C Motif) Receptor 4 Heteromerization in Vascular Smooth Muscle. Evans AE, Tripathi A, LaPorte HM, Brueggemann LI, Singh AK, Albee LJ, Byron KL, Tarasova NI, Volkman BF, Cho TY, Gaponenko V, Majetschak M. International journal of molecular sciences. 2016 17: (Flo, PLA; Mouse, Human)
Commercially available antibodies directed against a-adrenergic receptor subtypes and other G protein-coupled receptors with acceptable selectivity in flow cytometry experiments. Abhishek Tripathi, Vadim Gaponenko, Matthias Majetschak. Naunyn-Schmiedeberg's archives of pharmacology. 2016 Feb;389:243-8.
Customer Reviews (0)
Featured Products
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit
Applications:
IHC, IHC - Paraffin
Species:
Human, Horse
Applications:
IHC, IHC - Paraffin, Western blot
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/21/2024
Date Requested: 11/21/2024
