Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Probable GTPase-activating protein for Rab8; its transient association with Rab8 is mediated by OPTN. Inhibits Rab8-mediated endocytic trafficking, such as of transferrin receptor (TfR) and reduces Rab8 recruitnment to tubules emanating from the endocytic recycling compartment (ERC). Involved in regulation of autophagy. Mediates inhibition of autophagy caused by the OPTN variant GLC1E LYS-50; the function requires its catalytic activity, however, the involved Rab is not known.
Gene Name: | TBC1 Domain Family, Member 17 |
Synonyms: | TBC1D17, TBC1 domain family member 17, TBC1 domain family, member 17 |
Target Sequences: | NM_024682 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.