SSTR2

somatostatin receptor 2

Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

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Products

ELISA Kits (8)

Type

Custom (5)

Sandwich (3)

Target

SSTR2 (8)

Reactivity

Human (3)

Mouse (1)

Rat (1)

Dog (1)

Pig (1)

Format

96-Well Microplate (1)

96-Well Strip Plate (7)

Publications

No (8)

Sample Type

Plasma (3)

Serum (3)

Tissue Homogenates (1)

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Human SSTR2 (Sandwich ELISA) ELISA Kit - LS-F24241

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

125 - 8000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Mouse SSTR2 (Sandwich ELISA) ELISA Kit - LS-F19697

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Human SSTR2 (Sandwich ELISA) ELISA Kit - LS-F35715

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Rat SSTR2 (Custom ELISA) ELISA Kit - LS-F19694

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Human SSTR2 (Custom ELISA) ELISA Kit - LS-F19695

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Bovine SSTR2 (Custom ELISA) ELISA Kit - LS-F19696

Type:

Custom

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Dog SSTR2 (Custom ELISA) ELISA Kit - LS-F19698

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Dog

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Pig SSTR2 (Custom ELISA) ELISA Kit - LS-F19699

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Pig

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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