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Plays a role in DNA double-strand break (DBS) repair via homologous recombination (HR). Serves as a scaffolding protein that helps to promote the recruitment of DNA-processing enzymes like the helicase BLM and recombinase RAD51 to site of DNA damage, and hence contributes to maintain genomic integrity.
Gene Name: | scaffolding protein involved in DNA repair |
Synonyms: | SPIDR, KIAA0146 |
Target Sequences: | D63480 BAA09767.1 Q14159 |
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