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The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the gamma-subunit protein. Alternatively spliced transcript variants encoding the same protein have been identified.
Gene Name: | Sec61 gamma subunit |
Synonyms: | SEC61G, Sec61 gamma subunit, SSS1 |
Target Sequences: | NM_014302 NP_055117.1 P60059 |
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