RXTA / RXR-Alpha

retinoid X receptor, alpha

Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid. RXRA serves as a common heterodimeric partner for a number of nuclear receptors. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, the RXR-RAR heterodimers associate with a multiprotein complex containing transcription corepressors that induce histone acetylation, chromatin condensation and transcriptional suppression. On ligand binding, the corepressors dissociate from the receptors and associate with the coactivators leading to transcriptional activation. The RXRA/PPARA heterodimer is required for PPARA transcriptional activity on fatty acid oxidation genes such as ACOX1 and the P450 system genes.

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ELISA Kits (7)

Type

Custom (2)

Sandwich (5)

Target

RXTA / RXR-Alpha (7)

Reactivity

Human (3)

Mouse (3)

Rat (1)

Format

96-Well Strip Plate (7)

Publications

No (7)

Sample Type

Cell Lysates (1)

Plasma (3)

Serum (3)

Tissue Homogenates (3)

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Human RXTA / RXR-Alpha (Sandwich ELISA) ELISA Kit - LS-F38233

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Mouse RXTA / RXR-Alpha (Sandwich ELISA) ELISA Kit - LS-F8670

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Tissue Homogenates

Price:

1 Plate/$748

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Human RXTA / RXR-Alpha (Sandwich ELISA) ELISA Kit - LS-F9347

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$730

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Mouse RXTA / RXR-Alpha (Sandwich ELISA) ELISA Kit - LS-F12522

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Rat RXTA / RXR-Alpha (Custom ELISA) ELISA Kit - LS-F19107

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Human RXTA / RXR-Alpha (Custom ELISA) ELISA Kit - LS-F19108

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Mouse RXTA / RXR-Alpha (Sandwich ELISA) ELISA Kit - LS-F33350

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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