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Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins are GTPase-activating proteins for Gi (see GNAI1; MIM 139310) and Gq (see GNAQ; MIM 600998) class G-alpha proteins. They accelerate transit through the cycle of GTP binding and hydrolysis and thereby accelerate signaling kinetics and termination.
Gene Name: | regulator of G-protein signaling 21 |
Synonyms: | RGS21 |
Target Sequences: | NP_001034241.1 Q2M5E4 |
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