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RGS2

regulator of G-protein signaling 2, 24kDa

Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. May play a role in leukemogenesis. Plays a role in negative feedback control pathway for adenylyl cyclase signaling. Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein.

Gene Name: regulator of G-protein signaling 2, 24kDa
Family/Subfamily: Regulator of G-protein signalling , not assigned-Regulator of G-protein signalling
Synonyms: RGS2, G0S8
Target Sequences: NM_002923 NP_002914.1 P41220

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Products
Proteins (7)
Over-Expression Lysate (2)
Recombinant (5)
RGS2 (7)
No (7)
6His-SUMO, N-terminus (1)
GST (1)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (3)
Human (6)
293T Cells (1)
E. coli (2)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (2)
RGS2 Protein
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E. coli
6His-SUMO, N-terminus
40.4 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
RGS2 Protein - 12.5% SDS-PAGE of human RGS2 stained with Coomassie Blue
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Wheat Germ Extract
GST
50.8 kDa
10 µg/$479; 25 µg/$670
RGS2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
RGS2 Protein - Purified recombinant protein RGS2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
24.2 kDa
20 µg/$1,107
RGS2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
24.2 kDa
100 µg/$494
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293T Cells
Myc-DDK (Flag)
24.2 kDa
20 µg/$150
RGS2 Protein
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E. coli
His
10 µg/$298; 50 µg/$417; 20 µg/$367; 100 µg/$564; 250 µg/$985; 500 µg/$1,480
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).