RAPGEF3 / EPAC

Rap guanine nucleotide exchange factor (GEF) 3

Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP. Through simultaneous binding of PDE3B to RAPGEF3 and PIK3R6 is assembled in a signaling complex in which it activates the PI3K gamma complex and which is involved in angiogenesis. Plays a role in the modulation of the cAMP-induced dynamic control of endothelial barrier function through a pathway that is independent on Rho-mediated signaling. Required for the actin rearrangement at cell-cell junctions, such as stress fibers and junctional actin.

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Products

Proteins (8)

Type

Over-Expression Lysate (4)

Recombinant (4)

Target

RAPGEF3 / EPAC (8)

Publications

No (8)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (6)

Species

Human (6)

Source

293T Cells (2)

HEK 293 Cells (4)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human RAPGEF3 / EPAC Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88248

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

99.2 kDa

Price:

20 µg/$215

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Human RAPGEF3 / EPAC Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88250

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

99.2 kDa

Price:

20 µg/$150

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RAPGEF3 / EPAC Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G119257

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

99.2 kDa

Price:

100 µg/$710

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RAPGEF3 / EPAC Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100725

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

99.2 kDa

Price:

100 µg/$494

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Human RAPGEF3 / EPAC Protein (Recombinant GST, N-terminus) (aa772-881) - LS-G61498

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human RAPGEF3 / EPAC Protein (Recombinant GST) (Full Length) - LS-G32130

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

125.8 kDa

Price:

2 µg/$439

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Human RAPGEF3 / EPAC Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G70890

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

99.2 kDa

Price:

20 µg/$1,107

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Human RAPGEF3 / EPAC Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G70892

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

99.2 kDa

Price:

20 µg/$1,107

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