Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.
Gene Name: | RAN binding protein 1 |
Synonyms: | RANBP1, RAN binding protein 1, Ran-binding protein 1, HTF9A |
Target Sequences: | NM_002882 NP_002873.1 P43487 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.