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Rab effector protein acting as linker between gamma-adaptin, RAB4A or RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates nucleotide exchange on RAB5A. Can act as a ubiquitin ligase.
Gene Name: | RAB guanine nucleotide exchange factor (GEF) 1 |
Synonyms: | RABGEF1, Rabex-5, Rab5 GDP/GTP exchange factor, RABEX5, RAP1 |
Target Sequences: | NM_014504 NP_055319.1 Q9UJ41 |
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