PRG2 / Proteoglycan 2

proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)

PRG2 / Proteoglycan 2 is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. The encoded protein contains a peptide that displays potent antimicrobial activity against Gram-positive bacteria, Gram-negative bacteria, and fungi. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Products

Proteins (10)

Type

Over-Expression Lysate (2)

Recombinant (8)

Target

PRG2 / Proteoglycan 2 (10)

Publications

No (9)

Yes (1)

Tag

6His, C-terminus (2)

6His-SUMO, N-terminus (1)

GST, N-terminus (1)

His-GST (3)

His-MBP (1)

Myc-DDK (Flag) (2)

Species

Human (6)

Mouse (2)

Rat (1)

Source

293T Cells (1)

E. coli (5)

HEK 293 Cells (1)

Human Cells (1)

Mammalian Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (2)

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Human PRG2 / Proteoglycan 2 Protein (Recombinant 6His, C-terminus) (Leu17-Tyr222) - LS-G39203

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

24.6kD

Price:

10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157

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Human PRG2 / Proteoglycan 2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75739

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

25.23 kDa

Price:

20 µg/$150

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Mouse PRG2 / Proteoglycan 2 Protein (Recombinant His-GST) (aa37-215) - LS-G14093

(4.0) Rating

(1) Publication(s)

Source:

E. coli

Tag:

His-GST

Molecular Weight:

51.4 kDa

Price:

10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334

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Human PRG2 / Proteoglycan 2 Protein (Recombinant GST, N-terminus) (aa123-222) - LS-G59710

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

2 µg/$439

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PRG2 / Proteoglycan 2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99846

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

25.23 kDa

Price:

100 µg/$494

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Human PRG2 / Proteoglycan 2 Protein (Recombinant 6His, C-terminus) (Leu17-Tyr222) - LS-G140065

Source:

Mammalian Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

24.6 kDa

Price:

10 µg/$344; 50 µg/$584

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Human PRG2 / Proteoglycan 2 Protein (Recombinant 6His-SUMO, N-terminus) (aa106-222) - LS-G56015

Source:

E. coli

Tag:

6His-SUMO, N-terminus

Price:

100 µg/$1,128; 20 µg/$721

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Mouse PRG2 / Proteoglycan 2 Protein (Recombinant His-GST) (aa100-215) - LS-G14092

Source:

E. coli

Tag:

His-GST

Molecular Weight:

44.9 kDa

Price:

10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334

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Rat PRG2 / Proteoglycan 2 Protein (Recombinant His-GST) (aa80-219) - LS-G14094

Source:

E. coli

Tag:

His-GST

Molecular Weight:

47.6 kDa

Price:

10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334

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Human PRG2 / Proteoglycan 2 Protein (Recombinant His-MBP) (aa105-222) - LS-G14095

Source:

E. coli

Tag:

His-MBP

Molecular Weight:

60.5 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$707; 200 µg/$885; 1 mg/$1,994; 500 µg/$1,534; 5 mg/$3,095; 2 mg/$2,181

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