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PRELP / Prolargin

proline/arginine-rich end leucine-rich repeat protein

PRELP / Prolargin is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed.

Gene Name: proline/arginine-rich end leucine-rich repeat protein
Synonyms: PRELP, MST161, Prolargin, SLRR2A, MSTP161, Prolargin proteoglycan
Target Sequences: NM_002725 NP_002716.1 P51888

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Products
Proteins (7)
Over-Expression Lysate (4)
Recombinant (3)
PRELP / Prolargin (7)
No (7)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (5)
Human (5)
293T Cells (2)
HEK 293 Cells (3)
Wheat Germ Extract (2)
Purified (1)
PRELP / Prolargin Protein - 12.5% SDS-PAGE of human PRELP stained with Coomassie Blue
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Wheat Germ Extract
GST
70.2 kDa
2 µg/$439
PRELP / Prolargin Protein - Purified recombinant protein PRELP was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
41.6 kDa
20 µg/$1,107
PRELP / Prolargin Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
PRELP / Prolargin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
41.6 kDa
20 µg/$150
PRELP / Prolargin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
43.81 kDa
20 µg/$150
PRELP / Prolargin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
43.81 kDa
100 µg/$494
PRELP / Prolargin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
41.6 kDa
100 µg/$494
Viewing 1-7 of 7 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).