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The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression.
Gene Name: | protein phosphatase, Mg2+/Mn2+ dependent, 1G |
Family/Subfamily: | Protein Phosphatase , PP2C |
Synonyms: | PPM1G, Phosphatase fin13, PP2CG, PP2C-gamma, Protein phosphatase 1C, PP2C, gamma, PP2CGAMMA, PPM1C, PPP2CG, Protein phosphatase 2c gamma, Protein phosphatase 1G |
Target Sequences: | NM_002707 NP_002698.1 O15355 |
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