Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
PPAN is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan). SSF1 is known to be involved in the second step of mRNA splicing. Both SSF1 and ppan are essential for cell growth and proliferation. Exogenous expression of this gene was reported to reduce the anchorage-independent growth of some tumor cells. Read-through transcription of this gene with P2RY11/P2Y(11), an adjacent downstream gene that encodes an ATP receptor, has been found. These read-through transcripts are ubiquitously present and up-regulated during granulocyte differentiation.
Gene Name: | peter pan homolog (Drosophila) |
Synonyms: | PPAN, BXDC3, Peter Pan homolog, SSF, SSF2, Peter pan (Drosophila) homolog, Second-step splicing factor 1, Suppressor of sterile four 1, Suppressor of SWI4 1 homolog, Homolog of S. cerevisiae SSF1, Peter pan homolog (Drosophila), SSF-1, SSF1 |
Target Sequences: | NM_020230 NP_064615.3 Q9NQ55 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.