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May play a role in early endosome fusion upstream of RAB5, hence regulating receptor trafficking and fluid-phase transport. Enhances cellular sensitivity to TNF-induced apoptosis (PubMed:18288467).
Gene Name: | pleckstrin homology domain containing, family F (with FYVE domain) member 2 |
Synonyms: | PLEKHF2, Phafin-2, PHAFIN2, ZFYVE18 |
Target Sequences: | NM_024613 NP_078889.1 Q9H8W4 |
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