PH4 / P4HTM

prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)

Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.

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Products

Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

PH4 / P4HTM (4)

Publications

No (4)

Tag

GST (1)

His-SUMO (1)

Myc-DDK (Flag) (2)

Species

Human (3)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human PH4 / P4HTM Protein (Recombinant His-SUMO) (aa82-563) - LS-G21968

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

70.51 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human PH4 / P4HTM Protein (Recombinant GST) (Full Length) - LS-G34030

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

89.5 kDa

Price:

10 µg/$479; 25 µg/$670

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Human PH4 / P4HTM Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82125

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

56.5 kDa

Price:

20 µg/$215

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PH4 / P4HTM Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G102475

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

56.5 kDa

Price:

100 µg/$710

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