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PH / PAH
phenylalanine hydroxylase
PAH encodes the enzyme phenylalanine hydroxylase that is the rate-limiting step in phenylalanine catabolism. Deficiency of this enzyme activity results in the autosomal recessive disorder phenylketonuria.
| Gene Name: | phenylalanine hydroxylase |
| Synonyms: | PAH, Phe-4-monooxygenase, PKU1, PH, Phenylalanine 4-monooxygenase, Phe-4- monooxygenase, Phenylalanine hydroxylase, Phenylalanine-4-hydroxylase, PKU |
| Target Sequences: | NM_000277 NP_000268.1 P00439 |
Publications (1)
1
CRISPR/Cas9 generated knockout mice lacking phenylalanine hydroxylase protein as a novel preclinical model for human phenylketonuria10<sup> Genomic Medicine Unit, Sanofi, 49 New York Avenue, Framingham, MA, 01701, USA. Sirkka.Kyostio-Moore@sanofi.com. Kuldeep Singh , Cathleen S Cornell, Robert Jackson, Mostafa Kabiri, Michael Phipps, Mitul Desai, Robert Fogle, Xiaoyou Ying, Gulbenk Anarat-Cappillino, Sarah Geller, Jennifer Johnson, Errin Roberts, Katie Malley, Tim Devlin, Matthew DeRiso, Patricia Berthelette, Yao V Zhang, Susan Ryan, Srinivas Rao, Beth L Thurberg, Dinesh S Bangari, Sirkka Kyostio-Moore. Scientific reports. 2021 Mar;11:7254. [Full Text Article]
[PubMed:33790381]
[PMC:PMC8012645]
Related Antibodies: LS-C344145.
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ELISA Kits
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Development Kit
(1)
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Target
PH / PAH
(9)
Reactivity
Human
(5)
Mouse
(1)
Monkey
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Porcine
(1)
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DevKit DuoPlus
(1)
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12 x 8-Well Microstrips
(1)
96-Well Microplate
(1)
96-Well Strip Plate
(6)
Antibody Pair and Standard
(1)
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No
(9)
Sample Type
Cell Culture Supernatants
(2)
Cell Lysates
(3)
Plasma
(3)
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(3)
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(4)
Sandwich
96-Well Strip Plate
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
1 Plate/$730
Sandwich
96-Well Strip Plate
Human
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Sandwich
96-Well Microplate
Human
78.13 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
Sandwich CLIA
12 x 8-Well Microstrips
Human
15.625 - 1000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$748
Sandwich
96-Well Strip Plate
Monkey
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
Sandwich
96-Well Strip Plate
Porcine
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
Sandwich
96-Well Strip Plate
Rabbit
3.125 - 200 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
Development Kit
Antibody Pair and Standard
Human
3.12 - 200 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
500 Wells/$1,276; 1000 Wells/$1,903
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