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PFKL is the liver (L) subunit of an enzyme that catalyzes the conversion of D-fructose 6-phosphate to D-fructose 1,6-bisphosphate, which is a key step in glucose metabolism (glycolysis). This enzyme is a tetramer that may be composed of different subunits encoded by distinct genes in different tissues. Alternative splicing results in multiple transcript variants.
Gene Name: | phosphofructokinase, liver |
Synonyms: | PFKL, Phosphofructokinase 1, Phosphofructokinase, liver, PFK-B, Phosphohexokinase |
Target Sequences: | NM_002626 NP_002617.3 P17858 |
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