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PEBP1 / RKIP

phosphatidylethanolamine binding protein 1

Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase By similarity. Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation.

Gene Name: phosphatidylethanolamine binding protein 1
Synonyms: PEBP1, HCNP, HCNPpp, PBP, Prostatic binding protein, Raf kinase inhibitor protein, Raf kinase inhibitory protein, Prostatic-binding protein, Neuropolypeptide h3, PEBP, PEBP-1, RKIP
Target Sequences: NM_002567 NP_002558.1 P30086

Publications (2)

1
GIT2 Acts as a Systems-Level Coordinator of Neurometabolic Activity and Pathophysiological Aging. Martin B, Chadwick W, Janssens J, Premont RT, Schmalzigaug R, Becker KG, Lehrmann E, Wood WH, Zhang Y, Siddiqui S, Park SS, Cong WN, Daimon CM, Maudsley S. Frontiers in endocrinology. 2016 6:191. (ICC, WB; Mouse, Human) [Full Text Article] [PubMed:26834700] [PMC:PMC4716144]
2
A proteomic view of isoproterenol induced cardiac hypertrophy: prohibitin identified as a potential biomarker in rats. Chowdhury D, Tangutur AD, Khatua TN, Saxena P, Banerjee SK, Bhadra MP. Journal of translational medicine. 2013 11:130. (IHC, WB; Human) [Full Text Article] [PubMed:23706090] [PMC:PMC3667141] Related Antibodies: LS-B3247.

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Proteins (7)
Over-Expression Lysate (2)
Recombinant (5)
PEBP1 / RKIP (7)
No (7)
GST (1)
His (1)
His-T7 (1)
Myc-DDK (Flag) (3)
Human (5)
Mouse (1)
293T Cells (1)
E. coli (3)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
Low endotoxin level (1)
PEBP1 / RKIP Protein
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E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
100 µg/$317; 500 µg/$526; 20 µg/$245
PEBP1 / RKIP Protein - 12.5% SDS-PAGE of human PBP stained with Coomassie Blue
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Wheat Germ Extract
GST
46.31 kDa
10 µg/$479; 25 µg/$670
PEBP1 / RKIP Protein - Purified recombinant protein PEBP1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
20.9 kDa
20 µg/$1,107
PEBP1 / RKIP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
20.9 kDa
20 µg/$150
PEBP1 / RKIP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
20.9 kDa
100 µg/$494
PEBP1 / RKIP Protein - Recombinant  Phosphatidylethanolamine Binding Protein 1 By SDS-PAGE
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E. coli
His-T7
24.6 kDa
10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231
PEBP1 / RKIP Protein - Recombinant Phosphatidylethanolamine Binding Protein 1 By SDS-PAGE
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E. coli
His
24.4 kDa
10 µg/$287; 50 µg/$480; 100 µg/$767; 200 µg/$957; 1 mg/$2,089; 500 µg/$1,617; 5 mg/$3,347; 2 mg/$2,278
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).