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PEBP1 / RKIP

phosphatidylethanolamine binding protein 1

Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase By similarity. Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation.

Gene Name: phosphatidylethanolamine binding protein 1
Synonyms: PEBP1, HCNP, HCNPpp, PBP, Prostatic binding protein, Raf kinase inhibitor protein, Raf kinase inhibitory protein, Prostatic-binding protein, Neuropolypeptide h3, PEBP, PEBP-1, RKIP
Target Sequences: NM_002567 NP_002558.1 P30086

Publications (2)

1
GIT2 Acts as a Systems-Level Coordinator of Neurometabolic Activity and Pathophysiological Aging. Martin B, Chadwick W, Janssens J, Premont RT, Schmalzigaug R, Becker KG, Lehrmann E, Wood WH, Zhang Y, Siddiqui S, Park SS, Cong WN, Daimon CM, Maudsley S. Frontiers in endocrinology. 2016 6:191. (ICC, WB; Mouse, Human) [Full Text Article] [PubMed:26834700] [PMC:PMC4716144]
2
A proteomic view of isoproterenol induced cardiac hypertrophy: prohibitin identified as a potential biomarker in rats. Chowdhury D, Tangutur AD, Khatua TN, Saxena P, Banerjee SK, Bhadra MP. Journal of translational medicine. 2013 11:130. (IHC, WB; Human) [Full Text Article] [PubMed:23706090] [PMC:PMC3667141] Related Antibodies: LS-B3247.

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Products
Antibodies (82)
Primary (82)
PEBP1 / RKIP (82)
Human (79)
Mouse (43)
Rat (9)
Bovine (11)
Chicken (4)
Chimpanzee (3)
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Gibbon (3)
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Hamster (1)
Horse (4)
Monkey (13)
Orangutan (3)
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Rabbit (1)
Xenopus (3)
Zebrafish (3)
IHC (24)
IHC-P (8)
WB (77)
ELISA (34)
ICC (3)
IF (4)
IP (8)
Peptide-ELISA (6)
RnaIP (1)
rabbit (66)
mouse (13)
goat (3)
Product Group
IHCPlus (4)
IgG (37)
IgG1 (4)
IgG1,k (6)
IgG2a (1)
IgG2b,k (2)
monoclonal mc (13)
polyclonal pc (69)
2G2-1F1 (1)
AT4B11 (1)
OTI2D4 (2)
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APC Conjugated (6)
Azide-free (2)
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Unconjugated (41)
aa2-187 (16)
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aa105-154 (1)
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aa142-187 (1)
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aa175-187 (1)
aa70-83 (1)
aa89-138 (1)
No (81)
Yes (1)
PEBP1 / RKIP Antibody - Anti-PEBP1 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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PEBP1 / RKIP Goat anti-Human Polyclonal (aa70-83) Antibody
Rabbit, Dog, Bovine, Pig, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
PEBP1 / RKIP Antibody - Immunofluorescence analysis of HeLa cells using PEBP1 antibody. Blue: DAPI for nuclear staining.
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PEBP1 / RKIP Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, IP, RnaIP, WB
Unconjugated
20 µl/$275; 100 µl/$389
PEBP1 / RKIP Antibody - ICC/IF analysis of PEBP1 in HeLa cells line, monoclonal anti-human PEBP1 antibody (1:100) stained with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).
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PEBP1 / RKIP Mouse anti-Human Monoclonal (AT4B11) Antibody
Human
ELISA, ICC, WB
Unconjugated
50 µl/$303; 100 µl/$365
PEBP1 / RKIP Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
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PEBP1 / RKIP Rabbit anti-Human Polyclonal (aa137-167) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
PEBP1 / RKIP Antibody - Immunofluorescent analysis of RKIP staining in HepG2 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
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PEBP1 / RKIP Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
ICC, IF, WB
Unconjugated
100 µl/$299
PEBP1 / RKIP Antibody - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
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PEBP1 / RKIP Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$460
PEBP1 / RKIP Antibody - Anti-PEBP1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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PEBP1 / RKIP Goat anti-Human Polyclonal (aa175-187) Antibody
Chicken, Bovine, Hamster, Pig, Horse, Mouse, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
PEBP1 / RKIP Antibody - PBP monoclonal antibody (M01), clone 2G2-1F1. Western Blot analysis of PEBP1 expression in human kidney.
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PEBP1 / RKIP Mouse anti-Human Monoclonal (2G2-1F1) Antibody
Human
WB
Unconjugated
100 µg/$423
PEBP1 / RKIP Antibody - Anti-PEBP1 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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PEBP1 / RKIP Rabbit anti-Human Polyclonal (aa1-30) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
200 µl/$460
PEBP1 / RKIP Antibody - Immunohistochemistry of paraffin-embedded human thyroid tissue at dilution of 1:100
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PEBP1 / RKIP Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
PEBP1 / RKIP Antibody - PEBP1 / RKIP antibody. IHC(P): Rat Kidney Tissue.
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PEBP1 / RKIP Rabbit anti-Mouse Polyclonal (aa15-29) Antibody
Mouse, Rat
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
PEBP1 / RKIP Antibody - Immunohistochemistry of paraffin-embedded Human lung cancer using PEBP1 Polyclonal Antibody at dilution of 1:50.
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PEBP1 / RKIP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
PEBP1 / RKIP Antibody - Immunohistochemistry of paraffin-embedded Human colon cancer using PEBP1 Polyclonal Antibody at dilution of 1:40.
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PEBP1 / RKIP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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PEBP1 / RKIP Rabbit anti-Human Polyclonal (aa137-167) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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PEBP1 / RKIP Rabbit anti-Human Polyclonal (aa137-167) (Biotin) Antibody
Mouse, Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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PEBP1 / RKIP Rabbit anti-Human Polyclonal (aa137-167) (APC) Antibody
Mouse, Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
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PEBP1 / RKIP Rabbit anti-Human Polyclonal (aa1-30) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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PEBP1 / RKIP Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody
Mouse, Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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PEBP1 / RKIP Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody
Mouse, Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
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PEBP1 / RKIP Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody
Mouse, Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
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PEBP1 / RKIP Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody
Mouse, Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
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PEBP1 / RKIP Rabbit anti-Human Polyclonal (aa1-30) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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PEBP1 / RKIP Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
PEBP1 / RKIP Antibody - IHC testing of FFPE mouse brain with RKIP antibody at 1ug/ml. HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min followed by cooling at RT for 20 min.
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PEBP1 / RKIP Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC-P, WB
Unconjugated
100 µg/$575
PEBP1 / RKIP Antibody - Staining HeLa cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
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PEBP1 / RKIP Rabbit anti-Human Polyclonal Antibody
Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).