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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
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PDE4B
phosphodiesterase 4B, cAMP-specific
PDE4B is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms.
| Gene Name: | phosphodiesterase 4B, cAMP-specific |
| Family/Subfamily: | Phosphodiesterase , PDE - cAMP-specific |
| Synonyms: | PDE4B, Pde-ivb, PDE32, PDE4B5, PDEIVB, Phosphodiesterase 4b, DPDE4, PDE4B3 |
| Target Sequences: | NM_002600 NP_002591.2 Q07343 |
Publications (2)
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