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PDE4B
phosphodiesterase 4B, cAMP-specific
PDE4B is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms.
| Gene Name: | phosphodiesterase 4B, cAMP-specific |
| Family/Subfamily: | Phosphodiesterase , PDE - cAMP-specific |
| Synonyms: | PDE4B, Pde-ivb, PDE32, PDE4B5, PDEIVB, Phosphodiesterase 4b, DPDE4, PDE4B3 |
| Target Sequences: | NM_002600 NP_002591.2 Q07343 |
Publications (2)
1
Altered phosphorylation, electrophysiology, and behavior on attenuation of PDE4B action in hippocampus. Campbell SL, van Groen T, Kadish I, Smoot LHM, Bolger GB,. BMC neuroscience. 2017 18:77. (WB; Human)
[Full Text Article]
[PubMed:29197324]
Related Antibodies: LS-C173292.
2
PDE4B Is a Homeostatic Regulator of Cyclic AMP in Dendritic Cells. Amy M Chinn, Cristina Salmerón, Jihyung Lee, Krishna Sriram, Eyal Raz, Paul A Insel. Frontiers in pharmacology. 2022 April;13:833832. [Full Text Article]
[PubMed:35387344]
[PMC:PMC8977838]
Related Antibodies: LS-B11018.
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(57)
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(2)
PDE4B Mouse anti-Human Monoclonal (1D12) Antibody
Mouse, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$485
PDE4B Mouse anti-Human Monoclonal (OTI3A10) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
PDE4B Mouse anti-Human Monoclonal (Carrier-free) (OTI3A10) Antibody
Human
Flo, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
PDE4B Goat anti-Human Polyclonal (aa723-736) Antibody
Mouse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
PDE4B Mouse anti-Human Monoclonal (Carrier-free) (1D12) Antibody
Mouse, Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
PDE4B Mouse anti-Human Monoclonal (OTI2B6) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
PDE4B Mouse anti-Human Monoclonal (Carrier-free) (OTI2B6) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
PDE4B Rabbit anti-Human Polyclonal (aa467-516) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
PDE4B Rabbit anti-Human Polyclonal (aa467-516) (HRP) Antibody
Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
PDE4B Rabbit anti-Human Polyclonal (aa467-516) (Biotin) Antibody
Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
PDE4B Rabbit anti-Human Polyclonal (aa467-516) (FITC) Antibody
Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
PDE4B Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
IHC, IP, WB
Unconjugated
50 µl/$482
PDE4B Rabbit anti-Human Polyclonal (aa489-736) Antibody
Human
WB
Unconjugated
100 µl/$450
PDE4B Mouse anti-Human Monoclonal (OTI3B12) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
PDE4B Mouse anti-Human Monoclonal (Carrier-free) (OTI3B12) Antibody
Human
Flo, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
PDE4B Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$440; 100 µg/$480
PDE4B Rabbit anti-Human Polyclonal (aa189-217) Antibody
Human
ELISA, Flo, WB
Unconjugated
200 µl/$734
PDE4B Rabbit anti-Human Polyclonal (aa189-217) (Biotin) Antibody
Human
ELISA, Flo, WB
Biotin Conjugated
200 µl/$952
PDE4B Rabbit anti-Human Polyclonal (aa189-217) (FITC) Antibody
Human
ELISA, Flo, WB
FITC Conjugated
200 µl/$952
PDE4B Rabbit anti-Human Polyclonal (aa189-217) (PE) Antibody
Human
ELISA, Flo, WB
PE Conjugated
200 µl/$952
PDE4B Rabbit anti-Human Polyclonal (aa189-217) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, WB
HRP Conjugated, Azide-free
200 µl/$952
PDE4B Rabbit anti-Human Polyclonal (aa189-217) (APC) Antibody
Human
ELISA, Flo, WB
APC Conjugated
200 µl/$952
PDE4B Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
PDE4B Mouse anti-Human Monoclonal (OTI1B11) Antibody
Human
Flo, WB
Unconjugated
100 µl/$434
PDE4B Mouse anti-Human Monoclonal (Carrier-free) (OTI1B11) Antibody
Human
Flo, WB
Unconjugated, Carrier-free
100 µg/$511
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