Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
P2RX7 / P2X7 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria.
Gene Name: | purinergic receptor P2X, ligand-gated ion channel, 7 |
Family/Subfamily: | Ion Channel , P2X receptor |
Synonyms: | P2RX7, ATP receptor, p2X purinoceptor 7, p2X receptor 7, p2X7 purinoceptor, p2Z receptor, Purinergic receptor, p2RX7, p2X7, p2X7 receptor |
Target Sequences: | NM_002562 NP_002553.3 Q99572 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.