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NXF5 is one member of a family of nuclear RNA export factor genes. The encoded protein can bind RNA, and is implicated in mRNA nuclear export. However, this protein has lost several C-terminal protein domains found in other family members that are required for export activity, and may be an evolving pseudogene. Alternatively spliced transcript variants have been described, but most are candidates for nonsense-mediated decay (NMD) and may not express proteins in vivo.
Gene Name: | nuclear RNA export factor 5 |
Synonyms: | NXF5, Nuclear RNA export factor 5, TAP-like protein 1, TAPL-1, TAPL1 |
Target Sequences: | NM_032946 NP_116564.2 Q9H1B4 |
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