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NOL3 / ARC

nucleolar protein 3 (apoptosis repressor with CARD domain)

Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD domain containing cell death regulators include RAIDD, Apaf-1, caspase-9, and caspase-2. A novel CARD domain containing protein was recently identified and designated ARC for apoptosis repressor with CARD (1). ARC interacts with caspase-2 and -8 and inhibits enzymatic activity of caspase-8. ARC suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR-1 and DR3. ARC is phosphorylated by casein kinase II (CK2) and phosphorylation is necessary to prevent apoptosis.

Gene Name: nucleolar protein 3 (apoptosis repressor with CARD domain)
Family/Subfamily: Apoptosis , not assigned-Apoptosis
Synonyms: NOL3, Apoptosis repressor with CARD, CARD2, FCM, NOP, Nucleolar protein 3, Nucleolar protein of 30 kDa, MYP, NOP30
Target Sequences: NM_003946 NP_003937.1 O60936

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Products
Antibodies (29)
Primary (29)
NOL3 / ARC (29)
Human (29)
Mouse (11)
Rat (6)
Bat (1)
Monkey (1)
Rabbit (1)
IHC (15)
IHC-P (7)
WB (26)
ELISA (11)
ICC (4)
IF (8)
IP (1)
Peptide-ELISA (2)
rabbit (29)
Product Group
IHCPlus (3)
IgG (19)
polyclonal pc (29)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
Unconjugated (23)
C-Terminus (5)
aa1-208 (4)
130-210 aa, C-terminal (1)
Glu194 (1)
aa125-141 (1)
aa159-208 (1)
aa91-106 (1)
No (29)
NOL3 / ARC Antibody - Anti-NOL3 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.
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NOL3 / ARC Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, IHC-P, IP, WB
Unconjugated
1 Each/$485
NOL3 / ARC Antibody - Western blot analysis of ARC in HeLa whole cell lysates with ARC antibody at 1:500 dilution.
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NOL3 / ARC Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
0.1 mg/$460
NOL3 / ARC Antibody - IHC of paraffin-embedded HeLa xenograft, using NOL3 antibody at 1:500 dilution.
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NOL3 / ARC Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$450
NOL3 / ARC Antibody - Anti-NOL3 antibody IHC of human kidney, glomeruli. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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NOL3 / ARC Rabbit anti-Human Polyclonal (aa159-208) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
NOL3 / ARC Antibody - Immunohistochemical analysis of Nop30 staining in mouse heart formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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NOL3 / ARC Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
NOL3 / ARC Antibody - WB of NOL3 / ARC antibody. All lanes: Anti-NOL3 at 0.5ug/ml. Lane 1: SMMC Whole Cell Lysate at 40ug. Lane 2: A549 Whole Cell Lysate at 40ug. Lane 3: U87 Whole Cell Lysate at 40ug. Lane 4: HELA Whole Cell Lysate at 40ug. Lane 5: MCF-7 Whole Cell Lysate at 40ug. Lane 6: Rat Liver Tissue Lysate at 40ug. Predicted bind size: 24KD. Observed bind size: 24KD.
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NOL3 / ARC Rabbit anti-Human Polyclonal (aa91-106) Antibody
Rabbit, Rat, Bat, Human, Monkey
WB
Unconjugated
10 µg/$318; 100 µg/$470
NOL3 / ARC Antibody - 1:200 staining human brain tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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NOL3 / ARC Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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NOL3 / ARC Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$331
NOL3 / ARC Antibody - Western blot of Myp antibody
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NOL3 / ARC Rabbit anti-Human Polyclonal (130-210 aa, C-terminal) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
NOL3 / ARC Antibody - Anti-NOL3 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:1000.
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NOL3 / ARC Rabbit anti-Human Polyclonal (aa125-141) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
NOL3 / ARC Antibody - Immunohistochemistry of paraffin-embedded rat testis tissue.
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NOL3 / ARC Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
NOL3 / ARC Antibody - IHC of ARC (E194) pAb in paraffin-embedded human brain tissue.
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NOL3 / ARC Rabbit anti-Human Polyclonal (Glu194) Antibody
Mouse, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
NOL3 / ARC Antibody - Immunohistochemistry of ARC in human heart tissue with ARC antibody at 5 ug/ml.
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NOL3 / ARC Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
0.1 mg/$460
NOL3 / ARC Antibody - Western blot analysis of extracts of various cell lines, using NOL3 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 30s.
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NOL3 / ARC Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
NOL3 / ARC Antibody - Immunohistochemistry of paraffin-embedded human skeletal muscle tissue at dilution 1:100
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NOL3 / ARC Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
NOL3 / ARC Antibody - IHC image of NOL3 Antibody diluted at 1:800 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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NOL3 / ARC Rabbit anti-Human Polyclonal (aa1-208) Antibody
Mouse, Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
NOL3 / ARC Antibody - Western blot. All lanes: Nucleolar protein 3 antibody at 2 ug/ml. Lane 1: mouse skeletal muscle tissue Lane 2: HeLa whole cell lysate. Secondary antibody: goat polyclonal to rabbit at 1:10000 dilution. Predicted band size: 24 kDa. Observed band size: 24 kDa.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NOL3 / ARC Rabbit anti-Human Polyclonal (aa1-208) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
NOL3 / ARC Antibody - Western blot. All lanes: Nucleolar protein 3 antibody at 2 ug/ml. Lane 1: mouse skeletal muscle tissue Lane 2: HeLa whole cell lysate. Secondary antibody: goat polyclonal to rabbit at 1:10000 dilution. Predicted band size: 24 kDa. Observed band size: 24 kDa.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NOL3 / ARC Rabbit anti-Human Polyclonal (aa1-208) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
NOL3 / ARC Antibody - Western blot. All lanes: Nucleolar protein 3 antibody at 2 ug/ml. Lane 1: mouse skeletal muscle tissue Lane 2: HeLa whole cell lysate. Secondary antibody: goat polyclonal to rabbit at 1:10000 dilution. Predicted band size: 24 kDa. Observed band size: 24 kDa.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NOL3 / ARC Rabbit anti-Human Polyclonal (aa1-208) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
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NOL3 / ARC Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
100 µl/$386
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NOL3 / ARC Rabbit anti-Human Polyclonal Antibody
Human
ICC, WB
Unconjugated
100 µl/$577
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NOL3 / ARC Rabbit anti-Human Polyclonal Antibody
Human
ICC, WB
Unconjugated
50 µl/$491
NOL3 / ARC Antibody - Immunohistochemistry of paraffin-embedded Human lung cancer using NOL3 Polyclonal Antibody at dilution of 1:35.
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NOL3 / ARC Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
NOL3 / ARC Antibody - Western blot of Nop30 in mouse muscle tissue lysate with Nop30 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml.
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NOL3 / ARC Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
0.1 mg/$460
NOL3 / ARC Antibody - NOL3 antibody Western blot of Fetal Muscle lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NOL3 / ARC Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
Viewing 1-25 of 29 product results


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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).