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NDUFB6 is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I). Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Alternative splicing occurs at this locus and three transcript variants encoding distinct isoforms have been identified.
Gene Name: | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa |
Synonyms: | NDUFB6, B17, CI-B17, Complex I-B17, CI |
Target Sequences: | NM_002493 NP_002484.1 O95139 |
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