NDN / Necdin

necdin, melanoma antigen (MAGE) family member

Growth suppressor that facilitates the entry of the cell into cell cycle arrest. Functionally similar to the retinoblastoma protein it binds to and represses the activity of cell-cycle-promoting proteins such as SV40 large T antigen, adenovirus E1A, and the transcription factor E2F. Necdin also interacts with p53 and works in an additive manner to inhibit cell growth. Functions also as transcription factor and binds directly to specific guanosine-rich DNA sequences.

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Products

Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

NDN / Necdin (4)

Publications

No (4)

Tag

GST (1)

Myc-DDK (Flag) (3)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human NDN / Necdin Protein (Recombinant GST) (Full Length) - LS-G29451

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

62.5 kDa

Price:

10 µg/$479; 25 µg/$670

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Human NDN / Necdin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81540

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

35.9 kDa

Price:

20 µg/$150

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Human NDN / Necdin Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68145

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

35.9 kDa

Price:

20 µg/$1,107

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NDN / Necdin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99771

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

35.9 kDa

Price:

100 µg/$494

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