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MSX1

msh homeobox 1

MSX1 is a member of the muscle segment homeobox gene family. The encoded protein functions as a transcriptional repressor during embryogenesis through interactions with components of the core transcription complex and other homeoproteins. It may also have roles in limb-pattern formation, craniofacial development, particularly odontogenesis, and tumor growth inhibition. Mutations in this gene, which was once known as homeobox 7, have been associated with nonsyndromic cleft lip with or without cleft palate 5, Witkop syndrome, Wolf-Hirschom syndrome, and autosomoal dominant hypodontia.

Gene Name: msh homeobox 1
Synonyms: MSX1, ECTD3, Homeobox protein MSX-1, HOX7, Msh homeo box 1, Homeobox 7, OFC5, STHAG1, Msh homeobox homolog 1, Homeobox protein Hox-7, HYD1, Msh homeobox 1, Msh homeobox 1-like protein
Target Sequences: NM_002448 NP_002439.2 P28360

Publications (2)

1
Msx1 and Msx2 gene expression is downregulated in the cadmium-induced omphalocele in the chick model. Doi T, Puri P, Bannigan J, Thompson J. Journal of pediatric surgery. 2010 45:1187-91. (IHC-P; Chicken) [PubMed:20620318]
2
Differentiation of induced pluripotent stem cells into dental mesenchymal cells. Otsu K, Kishigami R, Oikawa-Sasaki A, Fukumoto S, Yamada A, Fujiwara N, Ishizeki K, Harada H. Stem cells and development. 2014 May;21:1156-64. [Full Text Article] [PubMed:22085204] Related Antibodies: LS-C47382.

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Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
MSX1 (5)
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GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
MSX1 Protein - 12.5% SDS-PAGE of human MSX1 stained with Coomassie Blue
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Wheat Germ Extract
GST
57.3 kDa
2 µg/$439
MSX1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
MSX1 Protein - Purified recombinant protein MSX1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
31.3 kDa
20 µg/$1,107
MSX1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
31.3 kDa
20 µg/$150
MSX1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
31.3 kDa
100 µg/$494
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).