MMP12

matrix metallopeptidase 12 (macrophage elastase)

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. It is thought that the protein encoded by this gene is cleaved at both ends to yield the active enzyme, but this processing has not been fully described. The enzyme degrades soluble and insoluble elastin. It may play a role in aneurysm formation and studies in mice suggest a role in the development of emphysema. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

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Products

Antibodies (97)

Type

Primary (97)

Target

MMP12 (97)

Reactivity

Human (42)

Mouse (21)

Rat (42)

Monkey (2)

Rabbit (11)

Application

IHC (14)

IHC-P (3)

WB (95)

ELISA (17)

ICC (3)

IF (3)

IP (2)

Peptide-ELISA (4)

Host

rabbit (88)

goat (1)

guinea pig (8)

Isotype

IgG (29)

Clonality

polyclonal pc (97)

Format

APC (7)

APC Conjugated (9)

Azide-free (1)

Biotin Conjugated (12)

Cy3 Conjugated (7)

Cy7 Conjugated (7)

FITC Conjugated (12)

HRP Conjugated (10)

PE Conjugated (9)

Unconjugated (31)

Epitope

aa270-362 (10)

aa100-286 (8)

aa20-99 (8)

aa286-464 (8)

aa290-469 (8)

aa294-473 (8)

aa372-463 (8)

aa391-420 (7)

Internal (2)

60-140 aa, Internal (1)

Asp411 (1)

C-terminal (1)

Cleaved-Glu106 (1)

aa313-323 (1)

aa362-411 (1)

aa428-444 (1)

aa432-466 (1)

aa87-136 (1)

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Publications

No (97)

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MMP12 Antibody (aa391-420) LS-C100442

Antibody:

MMP12 Rabbit anti-Human Polyclonal (aa391-420) Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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MMP12 Antibody (aa294-473) LS-C295305

Antibody:

MMP12 Rabbit anti-Mouse Polyclonal (aa294-473) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$301; 200 µl/$340; 500 µl/$470; 1 ml/$535; 2 ml/$698; 5 ml/$1,161

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MMP12 Antibody (aa294-473, Biotin) LS-C298561

Antibody:

MMP12 Rabbit anti-Mouse Polyclonal (aa294-473) (Biotin) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$311; 200 µl/$353; 500 µl/$496; 1 ml/$567; 2 ml/$769; 5 ml/$1,248

• Unconjugated
• Biotin

• Unconjugated
• Biotin

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MMP12 Antibody (aa270-362) LS-B17045

Antibody:

MMP12 Rabbit anti-Rat Polyclonal (aa270-362) Antibody

Reactivity:

Rat

Applications:

ICC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µl/$460

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MMP12 Antibody LS-C317639

Antibody:

MMP12 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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MMP12 Antibody (aa313-323) LS-C112929

Antibody:

MMP12 Goat anti-Human Polyclonal (aa313-323) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

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MMP12 Antibody (Internal) LS-C413409

Antibody:

MMP12 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$321

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MMP12 Antibody (Internal) LS-C352531

Antibody:

MMP12 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$299

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MMP12 Antibody (aa100-286) LS-C295307

Antibody:

MMP12 Rabbit anti-Rat Polyclonal (aa100-286) Antibody

Reactivity:

Rat

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206

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MMP12 Antibody LS-C488308

Antibody:

MMP12 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC, IHC-P

Format:

Unconjugated

Price:

100 µl/$412

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MMP12 Antibody LS-C408342

Antibody:

MMP12 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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MMP12 Antibody LS-C666806

Antibody:

MMP12 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$351

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MMP12 Antibody (C-terminal) LS-C384579

Antibody:

MMP12 Rabbit anti-Human Polyclonal (C-terminal) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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MMP12 Antibody (aa391-420) LS-C327848

Antibody:

MMP12 Rabbit anti-Human Polyclonal (aa391-420) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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MMP12 Antibody (aa391-420, Biotin) LS-C279304

Antibody:

MMP12 Rabbit anti-Human Polyclonal (aa391-420) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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MMP12 Antibody (aa391-420, FITC) LS-C279305

Antibody:

MMP12 Rabbit anti-Human Polyclonal (aa391-420) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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MMP12 Antibody (aa391-420, PE) LS-C279307

Antibody:

MMP12 Rabbit anti-Human Polyclonal (aa391-420) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

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MMP12 Antibody (aa391-420, Azide-free, HRP) LS-C279306

Antibody:

MMP12 Rabbit anti-Human Polyclonal (aa391-420) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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MMP12 Antibody (aa391-420, APC) LS-C279300

Antibody:

MMP12 Rabbit anti-Human Polyclonal (aa391-420) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• PE
• HRP, Azide-free
• APC

• Unconjugated
• Biotin
• FITC
• More...
  • PE
  • HRP, Azide-free
  • APC

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MMP12 Antibody (aa362-411) LS-C292239

Antibody:

MMP12 Rabbit anti-Human Polyclonal (aa362-411) Antibody

Reactivity:

Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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MMP12 Antibody (Asp411) LS-C177738

Antibody:

MMP12 Rabbit anti-Human Polyclonal (Asp411) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

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MMP12 Antibody LS-C490606

Antibody:

MMP12 Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$575

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MMP12 Antibody LS-C404140

Antibody:

MMP12 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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MMP12 Antibody (aa432-466) LS-C408144

Antibody:

MMP12 Rabbit anti-Mouse Polyclonal (aa432-466) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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MMP12 Antibody (Cleaved-Glu106) LS-C821712

Antibody:

MMP12 Rabbit anti-Human Polyclonal (Cleaved-Glu106) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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