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MFRP is a member of the frizzled-related protein family. The encoded protein plays an important role in eye development and mutations in this gene have been associated with nanophthalmos, posterior microphthalmia, retinitis pigmentosa, foveoschisis, and optic disc drusen. The protein is encoded by a bicistronic transcript which also encodes C1q and tumor necrosis factor related protein 5 (C1QTNF5).
Gene Name: | membrane frizzled-related protein |
Synonyms: | MFRP, RD6, MCOP5, NNO2 |
Target Sequences: | NM_031433 NP_113621.1 Q9BY79 |
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