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Possible role in modulating immune responses. Induces morphological changes including production of filopodia and microspikes when overexpressed in a variety of cell types and may be involved in dendritic cell maturation. Isoform 1 and isoform 2 have an inhibitory effect on lymphocyte proliferation.
Gene Name: | leukocyte specific transcript 1 |
Synonyms: | LST1, B144, D6S49E, Lymphocyte antigen 117, LST-1, Protein B144 |
Target Sequences: | NM_007161 AAB57724.1 O00453 |
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