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Regulates HCFC1 activity by modulating its subcellular localization. Overexpression of HCFC1R1 leads to accumulation of HCFC1 in the cytoplasm. HCFC1R1-mediated export may provide the pool of cytoplasmic HCFC1 required for import of virion-derived VP16 into the nucleus.
Gene Name: | host cell factor C1 regulator 1 (XPO1 dependent) |
Synonyms: | HCFC1R1, HPIP |
Target Sequences: | NM_017885 NP_060355.1 Q9NWW0 |
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