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Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Two transcript variants encoding different isoforms have been found for this gene.
Gene Name: | guanylate cyclase 1, soluble, alpha 2 |
Family/Subfamily: | Guanyl cyclase , not assigned-Guanyl cyclase |
Synonyms: | GUCY1A2, GC-SA2, GCS-alpha-2, GUCSA2, GUC1A2 |
Target Sequences: | NM_000855 NP_000846.1 P33402 |
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