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Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Stimulates ATPase activity of mt-HSP70. May also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70.
Gene Name: | GrpE-like 2, mitochondrial (E. coli) |
Synonyms: | GRPEL2, Mt-GrpE#2 |
Target Sequences: | Q8TAA5 Q8TAA5 |
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