Geminin

geminin, DNA replication inhibitor

Geminin is a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene are located on the short arm of chromosome 16.

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Proteins (9)

Type

Over-Expression Lysate (2)

Recombinant (7)

Target

Geminin (9)

Publications

No (9)

Tag

GST (1)

GST, N-terminus (1)

His (1)

His-GST (2)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Human (6)

Mouse (1)

Rat (1)

Source

293T Cells (1)

E. coli (4)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human Geminin Protein (Recombinant His) - LS-G3423

Source:

E. coli

Tag:

His

Price:

100 µg/$411; 500 µg/$985; 20 µg/$276

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Human Geminin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G90168

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

23.4 kDa

Price:

20 µg/$150

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Geminin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101353

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

23.4 kDa

Price:

100 µg/$494

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Human Geminin Protein (Recombinant GST) (Full Length) - LS-G33600

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

50 kDa

Price:

10 µg/$479; 25 µg/$670

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Human Geminin Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G71593

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

23.4 kDa

Price:

20 µg/$1,107

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Human Geminin Protein (Recombinant GST, N-terminus) (aa110-209) - LS-G62397

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human Geminin Protein (Recombinant His-GST) (aa1-209) - LS-G24904

Source:

E. coli

Tag:

His-GST

Molecular Weight:

53.6 kDa

Price:

10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998

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Mouse Geminin Protein (Recombinant His-GST) (aa1-206) - LS-G24905

Source:

E. coli

Tag:

His-GST

Molecular Weight:

53.3 kDa

Price:

10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231

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Rat Geminin Protein (Recombinant His-T7) (aa8-206) - LS-G24906

Source:

E. coli

Tag:

His-T7

Molecular Weight:

27.0 kDa

Price:

10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204

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