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Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Mediates VEGF-induced CDC42 activation. May regulate proangiogenic action of VEGF in vascular endothelial cells, including network formation, directional movement and proliferation. May play a role in regulating the actin cytoskeleton and cell shape.
Gene Name: | FYVE, RhoGEF and PH domain containing 5 |
Synonyms: | FGD5 |
Target Sequences: | NP_689749.3 Q6ZNL6 |
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