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FECH / Ferrochelatase

ferrochelatase

FECH / Ferrochelatase is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome 3.

Gene Name: ferrochelatase
Synonyms: FECH, FCE, Heme synthase, EPP, Heme synthetase, Protoheme ferro-lyase, Protoporphyria, Ferrochelatase, Ferrochelatase, mitochondrial
Target Sequences: NM_000140 NP_000131.2 P22830

Publications (2)

1
Silencing of ferrochelatase enhances 5-aminolevulinic acid-based fluorescence and photodynamic therapy efficacy. Teng L, Nakada M, Zhao SG, Endo Y, Furuyama N, Nambu E, Pyko IV, Hayashi Y, Hamada JI. British journal of cancer. 2011 104:798-807. (WB; Human) [Full Text Article] [PubMed:21304523] Related Antibodies: LS-C307514.
2
Ferrochelatase regulates retinal neovascularization. Sardar Pasha Sheik Pran Babu, Darcy White, Timothy W Corson. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2020 September;34:12419-12435. [Full Text Article] [PubMed:32716567] [PMC:PMC7726024 (ava] Related Antibodies: LS-C409953.

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FECH / Ferrochelatase ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$730
FECH / Ferrochelatase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$669
FECH / Ferrochelatase ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Tissue Homogenates
1 Plate/$783
FECH / Ferrochelatase ELISA Kit
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Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$669
FECH / Ferrochelatase ELISA Kit
Select
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$669
FECH / Ferrochelatase ELISA Kit
Select
Custom
96-Well Strip Plate
Chicken
Colorimetric - 450nm (TMB)
1 Plate/$783
FECH / Ferrochelatase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
FECH / Ferrochelatase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
FECH / Ferrochelatase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).