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CYP39A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is involved in the conversion of cholesterol to bile acids. Its substrates include the oxysterols 25-hydroxycholesterol, 27-hydroxycholesterol and 24-hydroxycholesterol. Alternate splicing results in multiple transcript variants.
Gene Name: | cytochrome P450, family 39, subfamily A, polypeptide 1 |
Family/Subfamily: | Cytochrome P450 , not assigned-Cytochrome P450 |
Synonyms: | CYP39A1, HCYP39A1, Oxysterol 7alpha-hydroxylase, Oxysterol 7-alpha-hydroxylase, Cytochrome P450 39A1 |
Target Sequences: | NM_016593 NP_057677.2 Q9NYL5 |
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