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Complement C8b

complement component 8, beta polypeptide

Complement C8b is one of the three subunits of the complement component 8 (C8) protein. C8 is composed of equimolar amounts of alpha, beta and gamma subunits, which are encoded by three separate genes. C8 is one component of the membrane attack complex, which mediates cell lysis, and it initiates membrane penetration of the complex. This protein mediates the interaction of C8 with the C5b-7 membrane attack complex precursor. In humans deficiency of this protein is associated with increased risk of meningococcal infections. Alternative splicing results in multiple transcript variants.

Gene Name: complement component 8, beta polypeptide
Synonyms: C8B, Complement C8B
Target Sequences: NM_000066 NP_000057.2 P07358

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Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
Complement C8b (6)
No (6)
His-T7 (3)
Myc-DDK (Flag) (3)
Human (3)
Mouse (1)
Rat (1)
293T Cells (1)
E. coli (3)
HEK 293 Cells (2)
Complement C8b Protein - Purified recombinant protein C8B was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
63.4 kDa
20 µg/$1,107
Complement C8b Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
67.05 kDa
20 µg/$215
Complement C8b Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
67.05 kDa
100 µg/$710
Complement C8b Protein - Recombinant  Complement Component 8b By SDS-PAGE
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E. coli
His-T7
43.0 kDa
10 µg/$292; 50 µg/$512; 100 µg/$817; 200 µg/$1,018; 1 mg/$2,168; 500 µg/$1,690; 5 mg/$3,571; 2 mg/$2,359
Complement C8b Protein - Recombinant Complement Component 8b By SDS-PAGE
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E. coli
His-T7
43.0 kDa
10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257
Complement C8b Protein - Recombinant Complement Component 8b By SDS-PAGE
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E. coli
His-T7
42.8 kDa
10 µg/$290; 50 µg/$500; 100 µg/$797; 200 µg/$997; 1 mg/$2,139; 500 µg/$1,662; 5 mg/$3,487; 2 mg/$2,329
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).