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CLIC2 is a chloride intracellular channel protein. Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. This protein may play a role in inhibiting the function of ryanodine receptor 2. A mutation in this gene is the cause of X-linked mental retardation-32.
Gene Name: | chloride intracellular channel 2 |
Family/Subfamily: | Ion Channel , Chloride channel - intracellular |
Synonyms: | CLIC2, CLIC2b, MRXS32, XAP121 |
Target Sequences: | NM_001289 NP_001280.3 O15247 |
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