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CLEC2B / AICL encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell activation antigen. An alternative splice variant has been described but its full-length sequence has not been determined. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.
Gene Name: | C-type lectin domain family 2, member B |
Synonyms: | CLEC2B, CLECSF2, AICL, IFNRG1, HP10085 |
Target Sequences: | NM_005127 NP_005118.2 Q92478 |
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